- Organic Synthesis: ‘Ca’-talysis
The Mainstream Research Topics of Our Interests are:
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- Allenes: Synthesis & Functionalization
- Dyotropic Rearrangements and Other 1,2-Rearrangements
- Mechanochemistry: Synthesis and Reactivity Studies of Strain-Driven Reactions
- Building block Synthesis: small to complex molecules from a-Imino Ketones /Green Chemistry
- C-H Functionalizations
- Propargyl Alcohols: Paving the Way to Diverse Structural Motifs and Exciting Reaction Paths.
Our research program focuses on developing sustainable synthetic strategies for the functionalization of allenes, alkynols, Enynes, and diverse small-molecule building blocks. We leverage earth-abundant catalysts and highly selective reaction pathways to synthesize complex, biologically relevant chemical entities.
1. Calcium Catalysis (Emerging Green Catalysis)
We are a pioneering research group exploring calcium salts as sustainable Lewis acid alternatives to traditional, toxic transition-metal catalysts. Calcium offers exceptional benefits for green chemistry:
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- High natural abundance
- Non-toxic and biodegradable profile
- Excellent moisture tolerance
By exploiting these properties, we have successfully implemented calcium catalysts across a wide range of organic transformations, advancing the field of sustainable chemical synthesis.
